if you mean in YaCy web interface, then yes, for sure.
there are skins in “Portal Design” to select. you can choose the one, which fits you most, or adapt one for yourself, changing it’s CSS file. see old wiki.
(while changing the css, it seemed to me that the new one was working only after the restart, as far as i remember)
I have the “dark” theme in use and I can see the /skins/dark.css file, but its contents aren’t obvious for me and I can’t see any details at the documentation, wiki etc.